Oso is a good example of a bunny who never overcame his wariness of people, despite socialization.
Oso and his half-brother, Whoppy, were my first bunnies. They were born about 3 weeks apart, same father, different (but related) mothers. I first met Oso when he was literally a few hours old. He was just a blind little cocktail weenie-sized baby. He and his bunny family originally belonged to my employer at the time, and the rabbits lived on the company's premises. Part of my job was to feed the bunnies when I got to work. I knew almost nothing of rabbits, but I did read up on them during my spare time. When the adult rabbits had babies, I offered to take a pair after they weaned, which I did just before I quit.
Oso lived with me for over 9 years. In all those 9+ years, he was convinced I was going to eat him. Grooming him was a nightmare. The couple times I needed to syringe feed him was a battle of epic proportions. I was scraping off liquid food from the walls and floors (and myself). He regarded me with suspicion, despite the fact I fed him, gave him treats and generally did not torment him with affection. This was just part of his personality, and I had to respect that. It forced me to look deeper and appreciate him for other reasons. He was a good friend to his half-brother, Whoppy. He bonded easily to the other bunnies in the group. He was good-natured with them and he was never aggressive, nor was he particularly destructive. He was a handsome boy, and every once in awhile, he would bonk me with his nose to let me know he thought I was OK for a human. Oso taught me that you need to accept each individual bunny for who they are.